Immune-Based Interventions Against Infectious Disease - Impact of a Phase I Center for Biomedical Research Excellence in Translational Infectious Diseases Immunology

Immune-Based Interventions Against Infectious Disease – Impact of a Phase I Center for Biomedical Research Excellence in Translational Infectious Diseases Immunology

In 2011, school from the University of Rhode Island (URI)’s Institute for Immunology and Informatics and Lifespan’s Center for International Health Research collaborated to develop a profitable utility for a Phase I Center of Biomedical Research Excellence across the scientific theme of translational infectious ailments immunology. From 2013 to 2020, this COBRE supported vital discoveries in analysis on dengue, HIV, and malaria, amongst different ailments, and facilitated the profession improvement of a number of unbiased Rhode Island (RI)-based early-stage investigators.

Our expertise illustrates each the potential and challenges for investigators with shared scientific pursuits to leverage the NIH COBRE program to boost cross-institutional interactions. There was a vital lower in lung transplant volumes through the first wave of the COVID-19 pandemic as a result of a mixture of decreased availability of donors and an imbalance between waitlist additions and inactivations.

SARS-CoV-2 an infection was subsequently related to an exuberant immune response that may result in the event of postinfectious fibrotic lung illness. Few lung transplants have been carried out in beforehand contaminated recipients and lengthy-time period outcomes stay unknown. Although the lung transplant quantity rebounded through the second wave, it’s unclear what the lengthy-time period results of healthcare useful resource limitation and public well being measures can have on transplant volumes in the longer term.

Outcomes after SARS-CoV-2 an infection in earlier lung transplant recipients seem like worse than most people, and, though an immunosuppressed state possible contributes to those outcomes, whether or not immunosuppression must be altered in these uncovered to or contaminated with SARS-CoV-2 stays unanswered in the absence of unequivocal information.

Severe allergic reactions after COVID-19 vaccination with the Pfizer/BioNTech vaccine in Great Britain and USA: Position assertion of the German Allergy Societies: Medical Association of German Allergologists (AeDA), German Society for Allergology and Clinical Immunology (DGAKI) and Society for Pediatric Allergology and Environmental Medicine (GPA)

Two staff of the National Health Service (NHS) in England developed extreme allergic reactions following administration of BNT162b2 vaccine in opposition to COVID-19 (coronavirus illness 2019). The British SmPC for the BNT162b2 vaccine already contains reference to a contraindication for use in people who’ve had an allergic response to the vaccine or any of its elements.

As a precautionary measure, the Medicines and Healthcare merchandise Regulatory Agency (MHRA) has issued interim steering to the NHS to not vaccinate in precept in “sufferers with extreme allergic reactions”. Allergic reactions to vaccines are very uncommon, however vaccine elements are recognized to trigger allergic reactions. BNT162b2 is a vaccine based mostly on an mRNA embedded in lipid nanoparticles and blended with different substances to allow its transport into the cells.

In the pivotal section III medical trial, the BNT162b2 vaccine was usually properly tolerated, however this massive medical trial, used to help vaccine approval by the MHRA and US Food and Drug Administration, excluded people with a “historical past of a extreme antagonistic response associated to the vaccine and/or a extreme allergic response (e.g., anaphylaxis) to a element of the examine remedy”.

Vaccines are acknowledged as one of the simplest public well being interventions. This repeated administration of a international protein (antigen) necessitates a cautious allergological historical past earlier than every utility and diagnostic clarification and a danger-profit evaluation earlier than every injection. Severe allergic reactions to vaccines are uncommon however could be life-threatening, and it’s prudent to boost consciousness of this hazard amongst vaccination groups and to take satisfactory precautions whereas extra expertise is gained with this new vaccine.

 Immune-Based Interventions Against Infectious Disease - Impact of a Phase I Center for Biomedical Research Excellence in Translational Infectious Diseases Immunology

COVID-19: Immunology, Immunopathogenesis and Potential Therapies

The Coronavirus Disease-2019 (COVID-19) imposed public well being emergency and affected tens of millions of individuals across the globe. As of January 2021, 100 million confirmed circumstances of COVID-19 together with greater than 2 million deaths had been reported worldwide. SARS-CoV-2 an infection causes extreme manufacturing of professional-inflammatory cytokines thereby resulting in the event of “Cytokine Storm Syndrome.” This situation outcomes in uncontrollable irritation that additional imposes a number of-organ-failure ultimately resulting in loss of life. SARS-CoV-2 induces unrestrained innate immune response and impairs adaptive immune responses thereby inflicting tissue injury.

Thus, understanding the foremost options and evolution of innate and adaptive immunity to SARS-CoV-2 is essential in anticipating COVID-19 outcomes and in growing efficient methods to regulate the viral unfold. In the current assessment, we exhaustively talk about the sequential key immunological occasions that happen throughout SARS-CoV-2 an infection and are concerned in the immunopathogenesis of COVID-19.

In addition to this, we additionally spotlight numerous therapeutic choices already in use similar to immunosuppressive medication, plasma remedy and intravenous immunoglobulins together with numerous novel potent therapeutic choices that must be thought of in managing COVID-19 an infection similar to conventional medicines and probiotics.

Coomassie brilliant blue R-250

CB0037 5g
EUR 58.7
  • Product category: Biochemicals/Indicators/Stains/Peptide/Protein Related

Coomassie brilliant blue R-250 2 xSolution

C462151 250ml
EUR 106.55
  • Product category: Biochemicals/Indicators/Stains/Peptide/Protein Related

Brilliant Blue G

C5579-100000 100 g
EUR 135
Description: Coomassie Brilliant Blue G-250 is used for protein staining in SDS-PAGE, Blue Native PAGE, and the Bradford Method, with high band visibility.

Brilliant Blue FCF

HY-D0915 500mg
EUR 108

Coomassie Brilliant Blue G250

abx090654-5g 5 g
EUR 189
  • Shipped within 5-10 working days.

Coomassie Brilliant Blue R250

abx090655-5g 5 g
EUR 189
  • Shipped within 5-10 working days.

OPTIONAL BLUE FILTER (497NM)

GDBL-BLUE 1/pk
EUR 1082
Description: Lab Equipment; Axygen Branded EQ

conversion screen uv/blue

VLFC26-BLUE ea
EUR 606

Coomassie brilliant blue G-250

20-abx082402
  • EUR 230.00
  • EUR 189.00
  • 25 g
  • 5 g
  • Shipped within 5-10 working days.

Coomassie brilliant blue G-250

20-abx082562
  • EUR 217.00
  • EUR 175.00
  • 25 g
  • 5 g
  • Shipped within 5-10 working days.

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA3800 1 Gal.
EUR 241

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA500 500 ml
EUR 90

Brilliant Cresyl Blue (0.3%, Alcoholic)

BCA999 1000 ml
EUR 116

Brilliant Cresyl Blue (C.I. 51010)

GT9275-10G 10 g
EUR 86

Brilliant Cresyl Blue (C.I. 51010)

GT9275-25G 25 g
EUR 110

Coomassie brilliant blue G-250

CB0038 25g
EUR 75.23
  • Product category: Biochemicals/Indicators/Stains/Peptide/Protein Related

Coomassie Brilliant Blue Fast Staining Solution

abx090652-200ml 200 ml
EUR 203
  • Shipped within 5-10 working days.

Coomassie Brilliant Blue Gel Staining Kit

abx090653-1Kit 1 Kit
EUR 189
  • Shipped within 5-10 working days.

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-100G 100 g
EUR 126

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-25G 25 g
EUR 62

Coomassie Brilliant Blue R250 (C.I. 42660)

GT3543-5G 5 g
EUR 46

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-100G 100 g
EUR 126

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-25G 25 g
EUR 62

Coomassie Brilliant Blue G250 (C.I. 42655)

GT0353-5G 5 g
EUR 46

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS3800 1 Gal.
EUR 241

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS500 500 ml
EUR 90

Brilliant Cresyl Blue (1.5% in 0.85% Saline)

BCS999 1000 ml
EUR 116

10G Coomassie Blue R-250

NAT1360 10G
EUR 103

1000UL BLUE TIPS, RACKED AND PRE-STERILIZED

T-1000-B-R-S 1000/pk
EUR 175
Description: Non Filter Tips; Pipette Tips - Axygen

1000UL BLUE TIPS COMPATIBLE WITH EPPENDORF AND SOCOREX PIPETTORS.

TE-1004-B-R 1152/pk
EUR 212
Description: Non Filter Tips; Pipette Tips - Axygen

Fluorescence Microscopy Aid

4400 3 ml
EUR 180.5
Description: This is Counter - Stain/Blocking Diluent with optimal formula for preparaiton of final dilutions of FITC conjugate prior to use in FA procedures.

Brilliant green

BB0242 25g
EUR 56.09
  • Product category: Biochemicals/Indicators/Stains/Biological Stains

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 158

1000UL MAXYMUM RECOVERY BLUE TIPS COMPATIBLE WITH EPPENDORF AND SOCOREX PIPETTORS.

TE-1004-B-L-R 1152/pk
EUR 219
Description: Non Filter Tips; Maxymum Recovery Pipette Tips - Axygen

1000UL PRE-STERILIZED BLUE TIPS COMPATIBLE WITH EPPENDORF AND SOCOREX PIPETTORS

TE-1004-B-R-S 1152/pk
EUR 231
Description: Non Filter Tips; Pipette Tips - Axygen

Human tenascin-R(TN-R)ELISA Kit

QY-E00282 96T
EUR 361

Rat tenascin-R(TN-R)ELISA Kit

QY-E10465 96T
EUR 361

Mouse tenascin-R(TN-R)ELISA Kit

QY-E21437 96T
EUR 361

1000UL BLUE TIPS, RACKED

T-1000-B-R 1000/pk
EUR 161
Description: Non Filter Tips; Pipette Tips - Axygen

BRILLIANT GREEN AGAR

B02-115-10kg 10 kg
EUR 1222

BRILLIANT GREEN AGAR

B02-115-2Kg 2 Kg
EUR 305

BRILLIANT GREEN AGAR

B02-115-500g 500 g
EUR 119

1000UL MAXYMUM RECOVERY BLUE TIPS COMPATIBLE WITH EPPENDORF AND SOCOREX PIPETTORS.

TE-1004-B-L-R-S 1152/pk
EUR 239
Description: Non Filter Tips; Maxymum Recovery Pipette Tips - Axygen

Blue Base for Dissecting Board

M625 1 ea.
EUR 200

BRILLIANT GREEN BILE AGAR

B02-122-10kg 10 kg
EUR 1267

BRILLIANT GREEN BILE AGAR

B02-122-2Kg 2 Kg
EUR 315

BRILLIANT GREEN BILE AGAR

B02-122-500g 500 g
EUR 122

Brilliant Green (C.I. 42040)

GT6123-100G 100 g
EUR 78

Brilliant Green (C.I. 42040)

GT6123-25G 25 g
EUR 46

Brilliant Crocein (C.I. 27290)

GT8393-100G 100 g
EUR 86

Brilliant Crocein (C.I. 27290)

GT8393-250G 250 g
EUR 150

Brilliant Crocein (C.I. 27290)

GT8393-50G 50 g
EUR 62

Blue ear pig virus ELISA Kit -

QY-E40015 96T
EUR 394

Rat Creatine kinase for muscle and brain (CKMB)

QY-E11888 96T
EUR 374

ECOS Blue (XL1-Blue

FYE107-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE107-80VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE108-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE108-80VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE109-10VL 100 µl x 10 vials Ask for price

ECOS Blue (XL1-Blue

FYE109-80VL 100 µl x 10 vials Ask for price

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-10kg 10 kg Ask for price

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-2kg 2kg Ask for price

BRILLIANT GREEN AGAR WITH SULFAPYRIDINE

B02-117-500g 500 g Ask for price

BRILLIANT GREEN BILE BROTH 2%

B02-118-10kg 10 kg
EUR 1022

BRILLIANT GREEN BILE BROTH 2%

B02-118-2Kg 2 Kg
EUR 261

BRILLIANT GREEN BILE BROTH 2%

B02-118-500g 500 g
EUR 107

Brilliant Black BN (C.I. 28440)

GT6953-100G 100 g
EUR 140

Brilliant Black BN (C.I. 28440)

GT6953-10G 10 g
EUR 54

Brilliant Black BN (C.I. 28440)

GT6953-25G 25 g
EUR 78

Cibacron Brilliant Red 3B-A

GT9393-25G 25 g
EUR 181

Cibacron Brilliant Red 3B-A

GT9393-5G 5 g
EUR 78

4-Ways Microtube and Centrifuge Tubes Racks, Blue

R023-B 1 UNIT
EUR 53.48
  • Product category: Labware/Tube Racks/Multipurpose

Power leads for HorizeBLOT-R

2322462 5unit
EUR 270

Monoclonal antibody for Ankyrin R

SMC-487D 0.1mg
EUR 353
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is not conjugated.

Monoclonal antibody for Ankyrin R

SMC-487D-A390 0.1mg
EUR 400
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 390.

Monoclonal antibody for Ankyrin R

SMC-487D-A488 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 488.

Monoclonal antibody for Ankyrin R

SMC-487D-A565 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 565.

Monoclonal antibody for Ankyrin R

SMC-487D-A594 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 594.

Monoclonal antibody for Ankyrin R

SMC-487D-A633 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 633.

Monoclonal antibody for Ankyrin R

SMC-487D-A655 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 655.

Monoclonal antibody for Ankyrin R

SMC-487D-A680 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 680.

Monoclonal antibody for Ankyrin R

SMC-487D-A700 0.1mg
EUR 399
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with ATTO 700.

Monoclonal antibody for Ankyrin R

SMC-487D-ALP 0.1mg
EUR 393
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Alkaline Phosphatase.

Monoclonal antibody for Ankyrin R

SMC-487D-APC 0.1mg
EUR 398
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with APC.

Monoclonal antibody for Ankyrin R

SMC-487D-APCCY7 0.1mg
EUR 470
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with APC/Cy7.

Monoclonal antibody for Ankyrin R

SMC-487D-BI 0.1mg
EUR 395
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Biotin.

Monoclonal antibody for Ankyrin R

SMC-487D-DY350 0.1mg
EUR 413
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Dylight 350.

Monoclonal antibody for Ankyrin R

SMC-487D-DY405 0.1mg
EUR 402
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Dylight 405.

Monoclonal antibody for Ankyrin R

SMC-487D-DY488 0.1mg
EUR 392
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Dylight 488.

Monoclonal antibody for Ankyrin R

SMC-487D-DY594 0.1mg
EUR 394
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Dylight 594.

Monoclonal antibody for Ankyrin R

SMC-487D-DY633 0.1mg
EUR 389
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Dylight 633.

Monoclonal antibody for Ankyrin R

SMC-487D-FITC 0.1mg
EUR 391
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with FITC.

Monoclonal antibody for Ankyrin R

SMC-487D-HRP 0.1mg
EUR 387
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with HRP.

Monoclonal antibody for Ankyrin R

SMC-487D-P594 0.1mg
EUR 406
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with PE/ATTO 594.

Monoclonal antibody for Ankyrin R

SMC-487D-PCP 0.1mg
EUR 398
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with PerCP.

Monoclonal antibody for Ankyrin R

SMC-487D-RPE 0.1mg
EUR 396
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
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Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with RPE.

Monoclonal antibody for Ankyrin R

SMC-487D-STR 0.1mg
EUR 397
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is conjugated with Streptavidin.

Monoclonal antibody for Ankyrin R

SMC-487S 0.012mg
EUR 65
  • Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral m
  • Show more
Description: A monoclonal antibody from clone S388A-10 against Human Ankyrin R. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R. The antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:1000). This MAb for Ankyrin R is not conjugated.

EMPTY REFILL RACK WITH LID FOR USE WITH P2/P10 GILSON-STYLE AND 200UL UNIVERSAL FIT INSERTS.

RFL-R 10/pk
EUR 93
Description: Non Filter Tips; Pipette Tips - Axygen

20UL CLEAR TIPS FOR PACKARDS PLATE TRACK, EVOLUTION AND MINI TRACK INSTRUMENTS.

PK-20-R 960/pk
EUR 252
Description: Robotic Tips; Robotic tips - Axygen

200UL CLEAR TIPS FOR PACKARDS PLATE TRACK, EVOLUTION AND MINI TRACK INSTRUMENTS.

PK-200-R 960/pk
EUR 285
Description: Robotic Tips; Robotic tips - Axygen

50UL CLEAR TIPS FOR PACKARDS PLATE TRACK, EVOLUTION AND MINI TRACK INSTRUMENTS.

PK-50-R 960/pk
EUR 249
Description: Robotic Tips; Robotic tips - Axygen

Human Tenascin R(TNR)ELISA Kit

QY-E03056 96T
EUR 361

ELISA kit for Human R-type pyruvate kinase (R-PK)

KTE62579-48T 48T
EUR 354
  • The protein encoded by R-PK is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocyti
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Description: Quantitative sandwich ELISA for measuring Human R-type pyruvate kinase (R-PK) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human R-type pyruvate kinase (R-PK)

KTE62579-5platesof96wells 5 plates of 96 wells
EUR 2252
  • The protein encoded by R-PK is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocyti
  • Show more
Description: Quantitative sandwich ELISA for measuring Human R-type pyruvate kinase (R-PK) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human R-type pyruvate kinase (R-PK)

KTE62579-96T 96T
EUR 572
  • The protein encoded by R-PK is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocyti
  • Show more
Description: Quantitative sandwich ELISA for measuring Human R-type pyruvate kinase (R-PK) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human Protein Kinase R(PKR)ELISA Kit

QY-E03858 96T
EUR 361

Human R-Spondin 3(RSPO3)ELISA Kit

QY-E04633 96T
EUR 361

Human R-Spondin 2(RSPO2)ELISA Kit

QY-E04634 96T
EUR 361

Human R-Spondin 1(RSPO1)ELISA Kit

QY-E04635 96T
EUR 361

R-S-R

5-01865 4 x 5mg Ask for price

(R,R)-Hymeglusin

B1244-1000
EUR 479

(R,R)-Hymeglusin

B1244-500
EUR 294

(R,R)-Dipamp

20-abx181460
  • EUR 690.00
  • EUR 370.00
  • 1 g
  • 250 mg
  • Shipped within 1-2 weeks.

(R,R)-THC

B6909-10 10 mg
EUR 583

0.5-10UL CLEAR TIPS FOR P2/P10, RACKED AND PRE-STERILIZED

T-300-R-S 960/pk
EUR 135
Description: Non Filter Tips; Pipette Tips - Axygen

1.5 AND 2.0ML PRE-STERILIZED INDIVIDUALLY WRAPPED BLUE PESTLE

PES-15-B-SI 100/pk
EUR 177
Description: Micro Tubes; Micro Tubes Push Cap- Axygen

1000UL BLUE TIPS COMPATIBLE WITH EPPENDORF AND SOCOREX PIPETTORS

TE-1004-B 500/pk
EUR 126
Description: Non Filter Tips; Pipette Tips - Axygen

Inoculating Loops and Needles, 1ul Blue, Sterile, 25/Bag

IL311-1 1PK, 25UNIT
EUR 51.62
  • Product category: Labware/Culture Related/Inoculating Loops/Needles

80 WELL RED MICROTUBE RACK FOR 1.5/2.0ML MICROTUBES

R-80-R 5/pk
EUR 94
Description: Micro Tubes; Racks Tubes - Axygen

4-Ways Microtube and Centrifuge Tubes Racks, Red

R023-R 1 UNIT
EUR 53.48
  • Product category: Labware/Tube Racks/Multipurpose

Phthalocyanine blue

20-abx181340
  • EUR 328.00
  • EUR 217.00
  • EUR 746.00
  • 100 g
  • 25 g
  • 500 g
  • Shipped within 1-2 weeks.

Evans Blue

abx186080-125g 125g
EUR 453
  • Shipped within 1-2 weeks.

Bromophenol blue

abx183916-500ml 500 ml
EUR 230
  • Shipped within 1-2 weeks.

Bromophenol blue

abx183916-5l 5l
EUR 592
  • Shipped within 1-2 weeks.

Evans Blue

20-abx082082
  • EUR 175.00
  • EUR 217.00
  • 1 g
  • 5 g
  • Shipped within 5-10 working days.

Bromphenol Blue

20-abx082184
  • EUR 230.00
  • EUR 189.00
  • 25 g
  • 5 g
  • Shipped within 5-10 working days.

Evans Blue

20-abx082237
  • EUR 189.00
  • EUR 230.00
  • 1 g
  • 5 g
  • Shipped within 5-10 working days.

Bromphenol Blue

20-abx082376
  • EUR 244.00
  • EUR 189.00
  • 25 g
  • 5 g
  • Shipped within 5-10 working days.

Toluidine Blue

abx082425-5g 5 g
EUR 189
  • Shipped within 5-10 working days.

Trypan Blue

20-abx082476
  • EUR 230.00
  • EUR 189.00
  • 25 g
  • 5 g
  • Shipped within 5-10 working days.

Bromophenol Blue

abx082607-10g 10 g
EUR 203
  • Shipped within 5-10 working days.

Peptides that bind to and are offered on the cell floor by Human Leukocyte Antigens (HLA) molecules play a crucial position in adaptive immunity. For a very long time, it was believed all of the HLA certain peptides had been generated by means of easy proteolysis of linear sequences of mobile proteins, and subsequently, are templated in the genome and proteome.

However, proof for untemplated peptide ligands of HLA molecules has amassed over the past 20 years, with a latest world evaluation of HLA-certain peptides suggesting that a appreciable proportion of HLA certain peptides are probably generated by means of splicing/fusion of discontinuous peptide segments from one or two distinct proteins.